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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent.

An RNA virus, designated hepatitis G virus (HGV), was identified from the plasma of a patient with chronic hepatitis. Extension from an immunoreactive complementary DNA clone yielded the entire genome (9392 nucleotides) encoding a polyprotein of 2873 amino acids. The virus is closely related to GB virus C (GBV-C) and distantly related to hepatitis C virus, GBV-A, and GBV-B. HGV was associated with acute and chronic hepatitis. Persistent viremia was detected for up to 9 years in patients with hepatitis. The virus is transfusion-transmissible. It has a global distribution and is present within the volunteer blood donor population in the United States.[1]

References

  1. Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Linnen, J., Wages, J., Zhang-Keck, Z.Y., Fry, K.E., Krawczynski, K.Z., Alter, H., Koonin, E., Gallagher, M., Alter, M., Hadziyannis, S., Karayiannis, P., Fung, K., Nakatsuji, Y., Shih, J.W., Young, L., Piatak, M., Hoover, C., Fernandez, J., Chen, S., Zou, J.C., Morris, T., Hyams, K.C., Ismay, S., Lifson, J.D., Hess, G., Foung, S.K., Thomas, H., Bradley, D., Margolis, H., Kim, J.P. Science (1996) [Pubmed]
 
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