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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Drug-induced changes in the plasma membrane of Microsporum canis. A preliminary freeze--fracture study.

Commercial solutions of clotrimazole, tolnaftate and tolcyclate were tested for 12 h in cultures of Microsporum canis. They induced modifications in particle distribution, a blebbing of particle-free areas and the appearance of lamellar figures on the plasma membrane of fungus cells. The first two changes in the plasma membrane might be ascribed to a modification of the spectrin-like meshwork, while the third could be the result of a crystalline organization of membrane lipids.[1]

References

  1. Drug-induced changes in the plasma membrane of Microsporum canis. A preliminary freeze--fracture study. Puccinelli, V., Innocenti, M., Lasagni, A., Caputo, R. Br. J. Dermatol. (1977) [Pubmed]
 
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