- Human endopeptidase (THOP1) is localized on chromosome 19 within the linkage region for the late-onset alzheimer disease AD2 locus. Meckelein, B., de Silva, H.A., Roses, A.D., Rao, P.N., Pettenati, M.J., Xu, P.T., Hodge, R., Glucksman, M.J., Abraham, C.R. Genomics (1996)









