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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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False-positive iodine-131 whole-body scans due to cholecystitis and sebaceous cyst.

False-positive whole-body 131I scans are not frequent but have serious consequences in the management of patients with thyroid cancer. They can be classified in four main groups: elimination of iodine in body fluids, infection or inflammation, cysts or transudates and nonthyroid tumors. We report on two patients with false-positive post-therapy 131I scans. The first patient had uptake projected in the right pelvic area which was later proven to be a large gluteal sebaceous cyst. The second patient had uptake in the gallbladder area that did not disappear after 131I treatment; she underwent exploratory laparotomy which revealed extensive chronic cholecystitis. These cases illustrate two new causes of false-positive 131I whole-body scans (sebaceous cyst and cholecystitis), which highlights two mechanisms (elimination in body fluid and inflammation).[1]

References

  1. False-positive iodine-131 whole-body scans due to cholecystitis and sebaceous cyst. Brucker-Davis, F., Reynolds, J.C., Skarulis, M.C., Fraker, D.L., Alexander, H.R., Weintraub, B.D., Robbins, J. J. Nucl. Med. (1996) [Pubmed]
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