- The FHIT and PTPRG genes are deleted in benign proliferative breast disease associated with familial breast cancer and cytogenetic rearrangements of chromosome band 3p14. Panagopoulos, I., Pandis, N., Thelin, S., Petersson, C., Mertens, F., Borg, A., Kristoffersson, U., Mitelman, F., Aman, P. Cancer Res. (1996)