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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Effect of natural food colorings on immunoglobulin production in vitro by rat spleen lymphocytes.

Water-soluble (cacao pigment, cochineal pigment, corn pigment, betanin, carthamus yellow, and monascus pigment) and water-insoluble (gardenia yellow, laccaic acid, bixin, and curcumin) natural colorings inhibited IgE production by rat spleen lymphocytes at 10 and microM, respectively. Although many of these colorings only inhibited the production of IgG and IgM at high concentrations, the water-insoluble colorings enhanced IgM production even at 1 microM. These results suggest that natural colorings have immunoglobulin production-regulating activity.[1]

References

  1. Effect of natural food colorings on immunoglobulin production in vitro by rat spleen lymphocytes. Kuramoto, Y., Yamada, K., Tsuruta, O., Sugano, M. Biosci. Biotechnol. Biochem. (1996) [Pubmed]
 
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