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Oh, Y. et al.

Expression of the amiloride-sensitive sodium channel beta subunit gene in human B lymphocytes.

The amiloride-sensitive, epithelial sodium channel (ENaC) is composed of at least three subunits (alpha, beta, and gamma). This study demonstrates that the ENaC beta subunit gene is expressed in human B cell lines, peripheral blood lymphocytes, and lymph node at the mRNA level. Further, this study shows that both wild-type and mutated alleles of the ENaC beta subunit gene are transcribed in human B lymphocytes derived from an individual affected with Liddle's syndrome, an autosomal dominant form of human hypertension.[1]

References

Expression of the amiloride-sensitive sodium channel beta subunit gene in human B lymphocytes. Oh, Y., Warnock, D.G. J. Am. Soc. Nephrol. (1997) [Pubmed]

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