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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Molecular cloning and chromosomal localization in human and mouse of the SH2-containing inositol phosphatase, INPP5D (SHIP). Amgen EST Program.

The action of lipid phosphatases on inositol phosphates is thought to be one method that the cell uses to attenuate growth factor- or cytokine-induced mobilization of calcium. We have cloned a cDNA from a mouse spleen library that is virtually identical to the recently described inositol tetraphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase, SHIP. Chromosomal localization studies in human and mouse by FISH mapping and interspecies backcrossing in mice have demonstrated that human SHIP is localized to 2q36-q37.1 and that mouse SHIP is localized to 1C5.[1]

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