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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Cyclosporin for thrombotic thrombocytopenic purpura after autologous bone marrow transplantation.

Thrombotic thrombocytopenic purpura (TTP) after bone marrow transplantation (BMT) is a serious complication that, in contrast to classic TTP, is generally not responsive to therapeutic plasma exchange. We describe the remission of TTP after autologous BMT by administration of cyclosporin in four patients, either after failure of plasmapheresis (two patients) or as primary treatment modality (two patients). Cyclosporin may be an attractive drug for post autologous BMT-TTP.[1]

References

  1. Cyclosporin for thrombotic thrombocytopenic purpura after autologous bone marrow transplantation. van Ojik, H., Biesma, D.H., Fijnheer, R., Hené, R.J., Lokhorst, H.M., Rooda, S.J., Verdonck, L.F. Br. J. Haematol. (1997) [Pubmed]
 
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