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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

cDNA cloning and immunological characterization of rabbit p53.

We have cloned and sequenced the p53-encoding rabbit cDNA (Oryctolagus cuniculus). The encoded product is 86% and 80% homologous to human and mouse p53, respectively. It features many characteristics found in all p53 proteins: (i) the five domains highly conserved during evolution, (ii) an acidic N terminus, (iii) a hydrophilic C terminus and (iv) a penultimate serine residue. Immunoprecipitation of the cDNA-encoded protein by monoclonal antibodies specific for mammalian p53 has confirmed the identity of the protein.[1]


  1. cDNA cloning and immunological characterization of rabbit p53. Le Goas, F., May, P., Ronco, P., Caron de Fromentel, C. Gene (1997) [Pubmed]
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