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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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An interactive Web site providing major histocompatibility ligand predictions: application to HIV research.

EpiMatrix/HIV, a tool that is currently available on the World Wide Web, enables researchers to screen HIV proteins for potential MHC ligands. We have performed a comparison of EpiMatrix predictions to 158 published allotype-specific HLA-associated peptides ( MHC ligands) derived from 133 proteins. The top 10 ranked EpiMatrix predictions for each of the 158 HLA allotype-protein pairs were selected for comparison with these published ligands. EpiMatrix correctly identified 134 of 158 published ligands (85%). The algorithm is now available for use by the HIV research community at the URL http:/(/)www.EpiMatrix.com/HIV.[1]

References

  1. An interactive Web site providing major histocompatibility ligand predictions: application to HIV research. De Groot, A.S., Jesdale, B.M., Szu, E., Schafer, J.R., Chicz, R.M., Deocampo, G. AIDS Res. Hum. Retroviruses (1997) [Pubmed]
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