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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Epidemiological features of testicular teratoma in a prepubertal population.

PURPOSE: Prepubertal teratomas of the testis are rare benign tumors. Knowledge of the epidemiology of testicular teratomas and associated alpha-fetoprotein ( AFP) levels could assist in planning treatment for prepubertal patients suspected of having teratoma of the testis. MATERIALS AND METHODS: We evaluated data on testicular teratoma from the Prepubertal Testis Tumor Registry of the Section on Urology of the American Academy of Pediatrics. RESULTS: Median patient age at presentation was 13 months. Teratomas occurred equally in the right and left testes. Most patients presented with a scrotal mass. Preoperative AFP levels were elevated in 20 of the 34 patients and postoperative levels were elevated in 9 of 10. Most patients were treated with radical orchiectomy and no metastatic disease was reported. CONCLUSIONS: Data in the registry confirm the benign nature of this tumor. Normal AFP levels should not be expected in infants with teratoma.[1]

References

  1. Epidemiological features of testicular teratoma in a prepubertal population. Grady, R.W., Ross, J.H., Kay, R. J. Urol. (1997) [Pubmed]
 
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