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Circular dichroism studies of imide derivatives of amines.

Circular dichroism curves have been measured for phthaloyl-, maleyl- and itaconyl-derivatives of a number of amines having a general formula R--CH(NH2)--R' (in which R and R' are alkyl-, aryl- or cyclohexyl-groups) and of 1,2,3,4-tetrahydro-1-naphthylamine and 1,2,3,4-tetrahydro-2-naphthylamine. We conclude that the determination of absolute configuration of amines examined can be made on the basis of C.D. curves of their phthaloyl-, maleyl- and itaconyl-derivatives, referring to that portion of the curve relating to the imide chromophore absorption.[1]

References

  1. Circular dichroism studies of imide derivatives of amines. Ghislandi, V., La Manna, A. Il Farmaco; edizione scientifica. (1976) [Pubmed]
 
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