Symptomatic carpal tunnel syndrome after orthotopic liver transplantation: a retrospective analysis.
BACKGROUND: Carpal tunnel syndrome ( CTS) is an entrapment neuropathy of the median nerve and has been reported after renal transplantation; there are no reports of CTS after liver transplantation. METHODS: The incidence of and the risk factors for CTS were assessed in 1350 liver allograft recipients. RESULTS: Seventeen women and two men with CTS were identified. Women developed symptoms at a median time of 6.8 months, and all but one received transplants because of primary biliary cirrhosis ( PBC). All 17 patients were taking cyclosporine. The only risk factor for CTS was the pretransplant diagnosis of PBC (6.7% of 240 PBC patients surviving 6 months or more compared with 0.4% of 717 patients who received grafts for other indications). CONCLUSIONS: CTS may occur in patients early after liver transplantation; because in many cases the symptoms were attributed to cyclosporine neurotoxicity, the diagnosis should be considered, especially in patients who received grafts because of PBC.[1]References
- Symptomatic carpal tunnel syndrome after orthotopic liver transplantation: a retrospective analysis. Grant, A.J., Buckels, J.A., Neuberger, J. Transplantation (1998) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg