Comparative study of the effects of several n-alkanes on phospholipid hexagonal phases.
The effects of a series of normal alkanes (decane, dodecane, tetradecane, hexadecane, and octadecane) on the hexagonal H(II) structures containing dioleoylphosphatidylethanolamine (DOPE) and dioleoylphosphatidylcholine (DOPC) were studied using x-ray diffraction and osmotic stress. The alkanes affect structural dimensions and the monolayer intrinsic curvature and bending modulus. The alkane effects are chain-length dependent and are attributed to their different distribution within the H(II) structure. The data suggest that short-chain alkanes are more uniformly distributed within the H(II) hydrocarbon regions and change the curvature and bending modulus of the monolayer, whereas longer-chain alkanes appear confined more to the interstitial region and do not change the curvature and bending modulus.[1]References
- Comparative study of the effects of several n-alkanes on phospholipid hexagonal phases. Chen, Z., Rand, R.P. Biophys. J. (1998) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
