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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Electron microscopic examination of Aedes albopictus clone C6/36 cells infected with dengue virus 2 at elevated incubation temperature.

Morphological changes such as loss of cytoplasm, membrane destruction and vacuolar swelling in Aedes albopictus clone C6/36 cells infected with dengue virus 2 (DV-2) New Guinea B strain and incubated at 28 degrees C and 37 degrees C, were observed under electron microscope. Both infected and uninfected cells showed significant damage at 37 degrees C in contrast to normal appearance at 28 degrees C. A higher number of virus particles were observed in the cytoplasm at 37 degrees C than at 28 degrees C.[1]

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