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Scheie, A.A. et al.

The effects of xylitol-containing chewing gums on dental plaque and acidogenic potential.

The aim of this study was to test the hypothesis that the chewing of xylitol- or xylitol/sorbitol-containing chewing gum reduces plaque formation and the acidogenic potential of dental plaque. Thirty healthy volunteers aged from 19 to 28 yrs were randomly allocated to one of three test groups, chewing either xylitol-, xylitol/sorbitol-, or sucrose-sweetened gums. A three-day plaque accumulation period of no oral hygiene was instituted prior to and at the termination of the chewing gum program, which lasted 33 days. Plaque quantity was assessed on the basis of protein content of individual plaque samples collected by a standardized technique. Acidogenic potential of individual baseline and test plaque samples was assessed by the quantity of various organic acids formed from D-(U-14C)glucose. Identification of extracellular and intracellular metabolites was performed by HPLC. Statistical evaluation of data was performed according to paired comparisons of individual baseline and post-chewing data. Plaque formation, acidogenic potential, and glycolytic profiles were similar at baseline and after the gum-chewing periods. Also, there was no intracellular accumulation of glycolytic metabolites within the plaque bacteria to indicate the inhibition of glycolysis. The study thus leads to the conclusion that, in young adults with low caries experience, exposure of the oral cavity to acceptable doses of xylitol or xylitol and sorbitol has no effect on the microbial deposits on the teeth.[1]

References

The effects of xylitol-containing chewing gums on dental plaque and acidogenic potential. Scheie, A.A., Fejerskov, O., Danielsen, B. J. Dent. Res. (1998) [Pubmed]

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