- Sequential intrahepatic fluorodeoxyuridine and systemic fluorouracil plus leucovorin for the treatment of metastatic colorectal cancer confined to the liver. O'Connell, M.J., Nagorney, D.M., Bernath, A.M., Schroeder, G., Fitzgibbons, R.J., Mailliard, J.A., Burch, P., Bolton, J.S., Colon-Otero, G., Krook, J.E. J. Clin. Oncol. (1998)