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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Profiling of 2-aminoacridone derivatised glycans by electrospray ionization mass spectrometry.

Three different types of N-glycans, high-mannose, complex and hybrid, have been derivatised with 2-aminoacridone and analysed by electrospray mass spectrometry and tandem mass spectrometry (MS/MS) using a hybrid quadrupole orthogonal acceleration time-of-flight mass spectrometer, fitted with a nanoflow electrospray ion source. Relatively simple MS/MS fragmentation patterns have been observed for each type of glycan, allowing rapid elucidation of the order in which the monosaccharide residues making up these glycans are linked to one another.[1]

References

  1. Profiling of 2-aminoacridone derivatised glycans by electrospray ionization mass spectrometry. Charlwood, J., Langridge, J., Tolson, D., Birrell, H., Camilleri, P. Rapid Commun. Mass Spectrom. (1999) [Pubmed]
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