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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Degs1  -  degenerative spermatocyte homolog 1...

Mus musculus

Synonyms: AA536663, Degenerative spermatocyte homolog 1, Degs, Des1, Mdes, ...
 
 
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High impact information on Degs1

  • Transcript levels of Des-2, but not Des-1, were considerably decreased in cultured keratinocytes from Arnt-null epidermis [1].
  • Based on these results, it is proposed that the products of Mdes and des have a phylogenetically conserved role in vertebrate and invertebrate spermatogenesis [2].

References

  1. Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function. Takagi, S., Tojo, H., Tomita, S., Sano, S., Itami, S., Hara, M., Inoue, S., Horie, K., Kondoh, G., Hosokawa, K., Gonzalez, F.J., Takeda, J. J. Clin. Invest. (2003) [Pubmed]
  2. Mdes, a mouse homolog of the Drosophila degenerative spermatocyte gene is expressed during mouse spermatogenesis. Endo, K., Matsuda, Y., Kobayashi, S. Dev. Growth Differ. (1997) [Pubmed]
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