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Gene Review

Bscl2  -  Berardinelli-Seip congenital lipodystrophy...

Mus musculus

Synonyms: 2900097C17Rik, AI046355, Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog, Gng3lg, MNCb-2630, ...
 
 
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High impact information on Bscl2

 

Biological context of Bscl2

 

Analytical, diagnostic and therapeutic context of Bscl2

  • Confirming the efficacy and specificity of gene targeting, Gng3-/- mice show no detectable expression of the Gng3 gene, but expression of the divergently transcribed Bscl2 gene is not affected [2].

References

  1. Structure and mapping of the G protein gamma3 subunit gene and a divergently transcribed novel gene, gng3lg. Downes, G.B., Copeland, N.G., Jenkins, N.A., Gautam, N. Genomics (1998) [Pubmed]
  2. Mice with deficiency of G protein gamma3 are lean and have seizures. Schwindinger, W.F., Giger, K.E., Betz, K.S., Stauffer, A.M., Sunderlin, E.M., Sim-Selley, L.J., Selley, D.E., Bronson, S.K., Robishaw, J.D. Mol. Cell. Biol. (2004) [Pubmed]
 
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