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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ccm2  -  cerebral cavernous malformation 2

Mus musculus

Synonyms: BC029157, Cerebral cavernous malformations protein 2 homolog, Malcavernin, Osm, Osmosensing scaffold for MEKK3
 
 
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High impact information on Ccm2

  • Beta-galactosidase activity in heterozygous brain and in situ hybridization in wild-type brain revealed Ccm2 expression in neurons and choroid plexus but not in vascular endothelium of small vessels in the brain [1].
  • RESULTS: In situ analysis shows similar temporal and spatial expression patterns for Ccm1 and Ccm2, although Ccm1 expression appears more widespread [2].
 

Other interactions of Ccm2

References

  1. Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations. Plummer, N.W., Squire, T.L., Srinivasan, S., Huang, E., Zawistowski, J.S., Matsunami, H., Hale, L.P., Marchuk, D.A. Mamm. Genome (2006) [Pubmed]
  2. CCM2 expression parallels that of CCM1. Seker, A., Pricola, K.L., Guclu, B., Ozturk, A.K., Louvi, A., Gunel, M. Stroke (2006) [Pubmed]
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