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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PDCD11  -  programmed cell death 11

Homo sapiens

Synonyms: ALG-4, ALG4, KIAA0185, NF-kappa-B-binding protein, NFBP, ...
 
 
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Disease relevance of PDCD11

  • Here, we report on the physical and functional interaction of NFBP, a recently identified protein that interacts with the P65 subunit of NF-kappaB, with HIV-1 Tat [1].
 

High impact information on PDCD11

  • Overexpression of full-length ALG-4 induced transcription of FasL and, consequently, apoptosis [2].

References

  1. Interplay between NFBP and NF-kappaB modulates tat activation of the LTR. Sweet, T., Sawaya, B.E., Khalili, K., Amini, S. J. Cell. Physiol. (2005) [Pubmed]
  2. Regulation of Fas ligand expression and cell death by apoptosis-linked gene 4. Lacana, E., D'Adamio, L. Nat. Med. (1999) [Pubmed]
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