Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

PSD3 - pleckstrin and Sec7 domain containing 3

Homo sapiens

Synonyms: DKFZp761K1423, EFA6D, EFA6R, Epididymis tissue protein Li 20mP, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, ...

Pils, D. et al., Stephanova, D.I. et al., van den Boom, J. et al.

Stephanova, Daskalova,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of PSD3

In addition, AMOG, DRR1 and PSD3 transcript levels were significantly lower in primary glioblastomas than in diffuse astrocytomas [1].
Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival [2].

High impact information on PSD3

RESULTS: Two genes showed a significantly (P< 0.05) lower expression in grade 3 tumors compared with tumors of lower grade (N33) or compared with normal controls and tumors with lower grade (EFA6R) [2].
RESULTS: Considerably reduced amplitudes, prolonged durations and slowed conduction velocities are obtained for the intracellular potentials of the PSD2 and PSD3 cases [3].
In addition, N33 and EFA6R showed a complete loss of expression in several ovarian cancer cell lines [2].

References

Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction. van den Boom, J., Wolter, M., Blaschke, B., Knobbe, C.B., Reifenberger, G. Int. J. Cancer (2006) [Pubmed]
Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival. Pils, D., Horak, P., Gleiss, A., Sax, C., Fabjani, G., Moebus, V.J., Zielinski, C., Reinthaller, A., Zeillinger, R., Krainer, M. Cancer (2005) [Pubmed]
Differences in potentials and excitability properties in simulated cases of demyelinating neuropathies. Part II. Paranodal demyelination. Stephanova, D.I., Daskalova, M. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

PSD3	Bos taurus
PSD3	Canis lupus familiaris
psd3l	Danio rerio
PSD3	Gallus gallus
PSD3	Macaca mulatta
Psd3	Mus musculus
PSD3	Pan troglodytes
Psd3	Rattus norvegicus
psd3	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.