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Gene Review:

CYP4X1 - cytochrome P450, family 4, subfamily X,...

Homo sapiens

Synonyms: CYPIVX1, Cytochrome P450 4X1, MGC40051, UNQ1929/PRO4404

Savas, U. et al., Bylund, J. et al.

Bylund, Zhang, Harder,

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High impact information on CYP4X1

CYP4X1 was predominantly expressed in trachea and aorta, whereas CYP4Z1 mRNA was preferentially expressed in mammary tissue [1].
In situ hybridization experiments suggest that CYP4X1 is mainly expressed in neurons in different regions, e.g., the brain stem, hippocampus, cortex, and cerebellum as well as in vascular endothelial cells [2].

Analytical, diagnostic and therapeutic context of CYP4X1

Northern blot analysis showed that CYP4X1 is highly and specifically expressed in the brain [2].

References

Conditional regulation of the human CYP4X1 and CYP4Z1 genes. Savas, U., Hsu, M.H., Griffin, K.J., Bell, D.R., Johnson, E.F. Arch. Biochem. Biophys. (2005) [Pubmed]
Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain. Bylund, J., Zhang, C., Harder, D.R. Biochem. Biophys. Res. Commun. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CYP714A1	Arabidopsis thaliana
CYP714A2	Arabidopsis thaliana
LOC100847677	Bos taurus
CYP4X1	Canis lupus familiaris
LOC709535	Macaca mulatta
Cyp4x1	Mus musculus
Os05g0482400	Oryza sativa Japonica Group
Os12g0119000	Oryza sativa Japonica Group
Os11g0119700	Oryza sativa Japonica Group
Os07g0681300	Oryza sativa Japonica Group
Os03g0332000	Oryza sativa Japonica Group
LOC456833	Pan troglodytes
Cyp4x1	Rattus norvegicus

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