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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TIMM8B  -  translocase of inner mitochondrial...

Homo sapiens

Synonyms: DDP-like protein, DDP2, DDPL, Deafness dystonia protein 2, FLJ21744, ...
 
 
 
 
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High impact information on TIMM8B

  • Three subpopulations contained significantly elevated glutathione (GSH) levels by the factors 1.4 (DDP3), 1.7 (DDP2), and 2.4 (DDP4) compared to the maternal line (50.2 nM/mg protein) [1].
  • The 50% inhibitory drug concentration (IC50) of CDDP as determined by the colorimetric MTT-assay was increased by the factors 2.7 (DDP1), 3.3 (DDP2), 5.1 (DDP3), and 6.4 (DDP4) in the respective sublines [1].

References

  1. Establishment and characterization of cisplatin-resistant sublines of the human squamous carcinoma cell line HLac 79. Bier, H., Bergler, W., Mickisch, G., Wesch, H., Ganzer, U. Acta Otolaryngol. (1990) [Pubmed]
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