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GPR20  -  G protein-coupled receptor 20

Homo sapiens

Synonyms: G-protein coupled receptor 20
 
 
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High impact information on GPR20

 

Associations of GPR20 with chemical compounds

  • Knockdown of GPR20 in PC12h cells resulted in an elevation of the basal cAMP level, suggesting that the endogenous GPR20 achieves a constitutively or spontaneously active conformation [2].

References

  1. Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes. O'Dowd, B.F., Nguyen, T., Jung, B.P., Marchese, A., Cheng, R., Heng, H.H., Kolakowski, L.F., Lynch, K.R., George, S.R. Gene (1997) [Pubmed]
  2. Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins. Hase, M., Yokomizo, T., Shimizu, T., Nakamura, M. J. Biol. Chem. (2008) [Pubmed]
 
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