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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Zfp292  -  zinc finger protein 292

Mus musculus

Synonyms: 5730450D02Rik, 5830493J20Rik, 9430062L07Rik, AI449016, Krox-10, ...
 
 
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High impact information on Zfp292

  • Mouse growth hormone transcription factor Zn-16: unique bipartite structure containing tandemly repeated zinc finger domains not reported in rat Zn-15 [1].
  • Mouse Zn-16 mRNA also was detected by ribonuclease protection assay in the pre-somatotrophic mouse cell line GHFT1-5 [1].
  • Chromosomal localization of the zinc finger protein 15, Zfp15, on mouse chromosome 4 [2].
  • Correlation of GH mRNA abundance with transcription factor copy number showed a significant correlation for Pit-1, Prop-1, and Zn-16 [3].
 

Biological context of Zfp292

  • However, the mouse cDNA encodes 16 zinc fingers, and sequences of rZn-15 pituitary cDNAs were the same as the mouse (m) Zn-16; the rat sequence in GenBank has a one nucleotide offset of a 17-bp segment in the finger V region [1].
 

Other interactions of Zfp292

  • The cell extracts also showed an increased abundance of both Zn-16 and Pit-1 mRNAs when compared with whole pituitary extracts [3].
 

Analytical, diagnostic and therapeutic context of Zfp292

References

  1. Mouse growth hormone transcription factor Zn-16: unique bipartite structure containing tandemly repeated zinc finger domains not reported in rat Zn-15. VanderHeyden, T.C., Wojtkiewicz, P.W., Voss, T.C., Mangin, T.M., Harrelson, Z., Ahlers, K.M., Phelps, C.J., Hurley, D.L. Mol. Cell. Endocrinol. (2000) [Pubmed]
  2. Chromosomal localization of the zinc finger protein 15, Zfp15, on mouse chromosome 4. Roller, M.L., Camper, S.A. Mamm. Genome (1995) [Pubmed]
  3. Transcript abundance in mouse pituitaries with altered growth hormone expression quantified by reverse transcriptase polymerase chain reaction implicates transcription factor Zn-16 in gene regulation in vivo. Wojtkiewicz, P.W., Phelps, C.J., Hurley, D.L. Endocrine (2002) [Pubmed]
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