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Gene Review

Cht3  -  Chitinase 3

Drosophila melanogaster

Synonyms: BcDNA:LP04696, CG17682, CG18140, CG18140-PA3, CHT1, ...
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High impact information on Cht3

  • While the cathD insertion variant was detected only in the sequenced y; cn bw sp strain, the insertion variant present in the heterochromatic Cht3 gene was found to be fixed throughout twelve D. melanogaster populations and in a D. mauritiana strain suggesting that it maybe of adaptive significance [1].
  • A fragment of the Antonia long terminal repeat (LTR) retrotransposon is present in the intron of Chitinase 3 (Cht3), a gene located within the constitutive heterochromatin of chromosome 2L [1].


  1. Evidence for the adaptive significance of an LTR retrotransposon sequence in a Drosophila heterochromatic gene. McCollum, A.M., Ganko, E.W., Barrass, P.A., Rodriguez, J.M., McDonald, J.F. BMC Evol. Biol. (2002) [Pubmed]
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