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Gene Review:

KRTAP19-3 - keratin associated protein 19-3

Homo sapiens

Synonyms: GTHRP, GTRHP, Glycine/tyrosine-rich protein, KAP19.3, Keratin-associated protein 19-3

Marshall, R.C. et al., Emonet, N. et al., Ruangsittichai, J. et al.

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Disease relevance of KRTAP19-3

Opisthorchis viverrini: Identification of a glycine-tyrosine rich eggshell protein and its potential as a diagnostic tool for human opisthorchiasis [1].

High impact information on KRTAP19-3

Keratin associated proteins are classified into two groups (high-cysteine and high glycine-tyrosine-rich polypeptides) according to the content of these amino acids [2].
These polypeptides (about 32 chains) are organized into intermediate filaments (IFs) of 7.5 nm diameter which are embedded in variable amounts of a matrix of non-helical cystine-rich proteins and glycine-tyrosine-rich proteins [3].

References

Opisthorchis viverrini: Identification of a glycine-tyrosine rich eggshell protein and its potential as a diagnostic tool for human opisthorchiasis. Ruangsittichai, J., Viyanant, V., Vichasri-Grams, S., Sobhon, P., Tesana, S., Upatham, E.S., Hofmann, A., Korge, G., Grams, R. Int. J. Parasitol. (2006) [Pubmed]
Isolation and characterization of genomic clones of human sequences presumably coding for hair cysteine-rich proteins. Emonet, N., Michaille, J.J., Dhouailly, D. J. Dermatol. Sci. (1997) [Pubmed]
Structure and biochemistry of mammalian hard keratin. Marshall, R.C., Orwin, D.F., Gillespie, J.M. Electron Microsc. Rev. (1991) [Pubmed]

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