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Gene Review

ZNF260  -  zinc finger protein 260

Homo sapiens

Synonyms: OZRF1, PEX1, ZFP260, Zfp-260, Zfp260, ...
 
 
 
 
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Disease relevance of ZNF260

 

High impact information on ZNF260

  • Here, we describe the isolation by the yeast one-hybrid system of a cardiac cDNA encoding a novel nuclear zinc finger protein, Zfp260, belonging to the Krüppel family of transcriptional regulators [1].
  • Knockdown of Zfp260 in cardiac cells decreases endogenous ANF gene expression and abrogates its response to alpha1-adrenergic stimulation [1].

References

  1. The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling. Debrus, S., Rahbani, L., Marttila, M., Delorme, B., Paradis, P., Nemer, M. Mol. Cell. Biol. (2005) [Pubmed]
 
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