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Gene Review

TMEM189  -  transmembrane protein 189

Homo sapiens

Synonyms: KUA, Kua, Transmembrane protein 189
 
 
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Disease relevance of Kua

  • In this study we tried to elucidate the mechanisms by which vaccination of class I binding tumor peptides into an HLA-A2(+) lung cancer patient elicited dramatic amounts of IgG1 and IgG2 specific to a nonamer peptide, ubiquitin-conjugated enzyme variant Kua (UBE2V)(43-51) [1].
 

High impact information on Kua

References

  1. In vivo evidence that peptide vaccination can induce HLA-DR-restricted CD4+ T cells reactive to a class I tumor peptide. Harada, M., Gohara, R., Matsueda, S., Muto, A., Oda, T., Iwamoto, Y., Itoh, K. J. Immunol. (2004) [Pubmed]
  2. Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK. Poulin, F., Brueschke, A., Sonenberg, N. J. Biol. Chem. (2003) [Pubmed]
 
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