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Gene Review:

ANAPC7 - anaphase promoting complex subunit 7

Homo sapiens

Synonyms: APC7, Anaphase-promoting complex subunit 7, Cyclosome subunit 7

Park, K.H. et al.

Park, Choi, Eom, Kang,

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Disease relevance of ANAPC7

METHODS: The expression of APC7 was immunohistochemically investigated in 108 invasive ductal carcinomas of the breast and its relationship with clinicopathologic parameters was examined [1].
They therefore suggest that dysregulation of APC activity, possibly through downregulation of APC7, may be associated with tumorigenesis in breast cancer [1].

High impact information on ANAPC7

The frequency of APC7 negative expression was higher in high Ki-67 or aneuploid groups than in low Ki-67 or diploid groups [1].

References

Downregulation of the anaphase-promoting complex (APC)7 in invasive ductal carcinomas of the breast and its clinicopathologic relationships. Park, K.H., Choi, S.E., Eom, M., Kang, Y. Breast Cancer Res. (2005) [Pubmed]

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Os05g0149900	Oryza sativa Japonica Group
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