High impact information on ZNF71

• Among the 155 genes encoding zinc finger motif, the level of EST M88357 mRNA encoding a novel designated EZFIT (endothelial zinc finger protein induced by TNFalpha) was induced most profoundly (>19 fold) [1].
• The EZFIT gene is located on the chromosome 19q13 [1].
• EZFIT mRNA was not detected in the liver, lung, colon, stomach, the salivary gland or the thyroid gland [1].
• Among 24 human organs and cell types studied, EZFIT mRNA was found to be most highly expressed in the placenta followed by the brain, testis, pancreas, heart, small intestine, muscle, uterus, prostate and peripheral blood leukocytes [1].

Biological context of ZNF71

• 4. Isolation of the full length cDNA coding sequence by PCR using primers architected from the genomic sequence revealed that EZFIT has 490 amino acids which contain 13 C2H2 zinc finger motifs [1].

References