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Gene Review

MYO1G  -  myosin IG

Homo sapiens

Synonyms: HA-2, HA2, HLA-HA2, MHAG, Unconventional myosin-Ig
 
 
Myosin 1G (Myo1G) is a haematopoietic specific myosin that localises to the plasma membrane and regulates cell elasticity [1].
 

High impact information on MYO1G

 

Analytical, diagnostic and therapeutic context of MYO1G

  • RT-PCR amplification of MYO1G from different individuals led to the identification of two genetic variants, designated MYO1G(V) and MYO1G(M) [3].

References

  1. Myosin 1G (Myo1G) is a haematopoietic specific myosin that localises to the plasma membrane and regulates cell elasticity. Olety, B., Wälte, M., Honnert, U., Schillers, H., Bähler, M. FEBS. Lett. (2010) [Pubmed]
  2. Allele specific PCR for the minor Histocompatibility antigen HA-2. Wilke, M., Pool, J., Goulmy, E. Tissue Antigens (2002) [Pubmed]
  3. The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein. Pierce, R.A., Field, E.D., Mutis, T., Golovina, T.N., Von Kap-Herr, C., Wilke, M., Pool, J., Shabanowitz, J., Pettenati, M.J., Eisenlohr, L.C., Hunt, D.F., Goulmy, E., Engelhard, V.H. J. Immunol. (2001) [Pubmed]
 
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