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Gene Review

Sav1  -  salvador homolog 1 (Drosophila)

Mus musculus

Synonyms: 1700040G09Rik, 45 kDa WW domain protein, Protein salvador homolog 1, Salv, Sav, ...
 
 
 
 
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High impact information on Sav1

  • Originally identified in Drosophila melanogaster, the Warts(Wts)/Lats protein kinase has been proposed to function with two other Drosophila proteins, Hippo (Hpo) and Salvador (Sav), in the regulation of cell cycle exit and apoptosis [1].

References

  1. The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Chan, E.H., Nousiainen, M., Chalamalasetty, R.B., Schäfer, A., Nigg, E.A., Silljé, H.H. Oncogene (2005) [Pubmed]
 
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