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Gene Review

DEFB118  -  defensin, beta 118

Macaca mulatta

 
 
 
 
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High impact information on DEFB118

  • The most abundant, ESC42, contains a cysteine-rich region similar to the signature binding domain of the trefoil family of motogenic wound repair proteins [1].
  • The ESC42 gene, located on chromosome 20q11, contains two exons encoding two nearly identical predicted signal peptides and a third exon encoding the rest of the protein [1].

References

  1. Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human. Liu, Q., Hamil, K.G., Sivashanmugam, P., Grossman, G., Soundararajan, R., Rao, A.J., Richardson, R.T., Zhang, Y.L., O'Rand, M.G., Petrusz, P., French, F.S., Hall, S.H. Endocrinology (2001) [Pubmed]
 
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