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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Plxnd1  -  plexin D1

Mus musculus

Synonyms: 6230425C21Rik, Plexin-D1, b2b1863Clo, b2b553Clo
 
 
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High impact information on Plxnd1

  • Binding and complementary expression patterns of semaphorin 3E and plexin D1 in the mature neocortices of mice and monkeys [1].
  • We found that signaling by semaphorin 3E (Sema3E) and its receptor plexin-D1 controls endothelial cell positioning and the patterning of the developing vasculature in the mouse [2].
  • Sema3E is highly expressed in developing somites, where it acts as a repulsive cue for plexin-D1-expressing endothelial cells of adjacent intersomitic vessels [2].
 

Regulatory relationships of Plxnd1

References

  1. Binding and complementary expression patterns of semaphorin 3E and plexin D1 in the mature neocortices of mice and monkeys. Watakabe, A., Ohsawa, S., Hashikawa, T., Yamamori, T. J. Comp. Neurol. (2006) [Pubmed]
  2. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Gu, C., Yoshida, Y., Livet, J., Reimert, D.V., Mann, F., Merte, J., Henderson, C.E., Jessell, T.M., Kolodkin, A.L., Ginty, D.D. Science (2005) [Pubmed]
  3. Different requirement for Rnd GTPases of R-Ras GAP activity of Plexin-C1 and Plexin-D1. Uesugi, K., Oinuma, I., Katoh, H., Negishi, M. J. Biol. Chem. (2009) [Pubmed]
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