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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Rhox2a  -  reproductive homeobox 2A

Mus musculus

Synonyms: 4930539I12Rik, Rhox2, Rhox2.1
 
 
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High impact information on Rhox2

  • Molecular evolutionary analysis reveals that this cluster is an actively evolving region with Rhox2 and 4 paralogues under diversifying selection and Rhox3 evolving neutrally [1].
  • The biological importance of this duplication is emphasised by the identification of an important role for Rhox2 and Rhox4 in regulating the initial stages of embryonic stem (ES) cell differentiation [1].

References

  1. A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection. Jackson, M., Watt, A.J., Gautier, P., Gilchrist, D., Driehaus, J., Graham, G.J., Keebler, J., Prugnolle, F., Awadalla, P., Forrester, L.M. BMC Genomics (2006) [Pubmed]
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