The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

FERMT3  -  fermitin family member 3

Homo sapiens

Synonyms: Fermitin family homolog 3, KIND3, Kindlin-3, MGC10966, MIG-2, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of URP2

 

High impact information on URP2

  • Two additional kindlin proteins, kindlin-2 and kindlin-3, have also been described [2].
  • Finally, we have shown that the genomic structure for all three genes is nearly identical with all encoded by 15 exons although URP1 gene localized to chromosome 20p13, URP2 to 11q12 and MIG-2 to 14q22 [3].
  • In contrast, the expression of URP2 appears to be confined primarily to tissues of the immune system [3].
 

Anatomical context of URP2

 

Other interactions of URP2

  • We have also isolated the full-length clones for another novel related gene, URP2 and the previously discovered MIG-2 gene [3].

References

  1. Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B. Boyd, R.S., Adam, P.J., Patel, S., Loader, J.A., Berry, J., Redpath, N.T., Poyser, H.R., Fletcher, G.C., Burgess, N.A., Stamps, A.C., Hudson, L., Smith, P., Griffiths, M., Willis, T.G., Karran, E.L., Oscier, D.G., Catovsky, D., Terrett, J.A., Dyer, M.J. Leukemia (2003) [Pubmed]
  2. Kindler surprise: mutations in a novel actin-associated protein cause Kindler syndrome. White, S.J., McLean, W.H. J. Dermatol. Sci. (2005) [Pubmed]
  3. URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas. Weinstein, E.J., Bourner, M., Head, R., Zakeri, H., Bauer, C., Mazzarella, R. Biochim. Biophys. Acta (2003) [Pubmed]
 
WikiGenes - Universities