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Gene Review

MED26  -  mediator complex subunit 26

Homo sapiens

Synonyms: ARC70, Activator-recruited cofactor 70 kDa component, CRSP complex subunit 7, CRSP7, CRSP70, ...
 
 
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High impact information on CRSP7

  • CRSPs 34, 77 and 130 are new proteins, but the amino terminus of CRSP70 is homologous to elongation factor TFIIS [1].
  • Domain I is conserved in evolution from yeast to human species and is homologous to the transcription factors elongin A and CRSP70 [2].
 

Other interactions of CRSP7

References

  1. The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Ryu, S., Zhou, S., Ladurner, A.G., Tjian, R. Nature (1999) [Pubmed]
  2. Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70. Booth, V., Koth, C.M., Edwards, A.M., Arrowsmith, C.H. J. Biol. Chem. (2000) [Pubmed]
 
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