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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Concept Formation

 
 
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Disease relevance of Concept Formation

 

Psychiatry related information on Concept Formation

  • SPD subjects showed significant decrements in performance on the California Verbal Learning Test, a word-list learning measure which requires semantic clustering for more efficient performance, and on the Wisconsin Card Sort Test, a measure requiring concept formation, abstraction, and mental flexibility [2].
  • RESULTS: Group comparisons revealed impairments of DPD patients in comparison with HC with respect to verbal fluency, short-term memory and concept formation [3].
  • Often considered one of the more discriminating tests between normal and brain-damaged individuals, the Category Test has been described as a complex measure of new problem solving, logical analysis, concept formation, abstract reasoning, and mental efficiency [4].
 

High impact information on Concept Formation

  • RESULTS: Amphetamine improved performance on a measure of concept formation on the Wisconsin Card Sorting Test but did not result in changes in performance on tests of memory or attention [5].
  • Duration of NIDDM was associated with increased risk for poor performance on tests of verbal memory and concept formation [6].
  • With levodopa substitution the patients with dopa responsive dystonia improved clinically as well as in quantitative tests on hand tapping, verbal and performance IQ, concept formation, and set shifting abilities [7].
  • During the laboratory session, HR, SBP, DBP, and self-report of affective states were measured while subjects performed two cognitive tasks (mental arithmetic and concept formation) [8].
  • METHODS: Ten SCA8 patients and ten case-by-case matched control subjects underwent a comprehensive neuropsychological examination evaluating attention and information processing, concept formation, reasoning and executive functions, verbal production, memory and learning and visuoperceptual and -constructive functions [9].
 

Chemical compound and disease context of Concept Formation

  • The Freedom from Distractibility factor demonstrated a complex pattern of correlations and appeared to reflect a range of abilities including quantitative, language, attentional, and concept formation [10].
  • Factor 1 emphasizes tactile/spatial functions, Factor 2 emphasizes concept formation and visual/spatial abilities, Factor 3 reflects motor strength, Factor 4 emphasizes sensory perception, and Factor 5 reflects motor speed [11].
 

Gene context of Concept Formation

  • The NF1 neuropsychological profile is characterized by deficits in perceptual skills (visuospatial and visuoperceptual), executive functioning (planning and abstract concept formation), and attention (sustained and switching) [12].
  • A large effect size was found for Concept Formation and results of this study suggested that the Predominately Inattentive Type and Combined Type of ADHD had the most difficulty on this task, as shown by the significantly lower scores on the measure when compared to the control group and the Predominately Hyperactive-Impulsive Type [13].
  • The neurophysiological basis of learning, Part 2: Concept formation/abstraction, reasoning and executive functions--implications for SCI nurses [14].
  • Neuropsychological testing established defects in concept formation tasks including the Raven Progressive Matrices, the Leiter International Performance Scale, and the Wisconsin Card Sorting test, as well as long-term memory defects where cognitive reorganization was needed [15].
  • In order to assess the effects of anxious-depression on cerebral functioning performance on the Trail Making Test (Forms A and B) and on the Concept Formation subtest of the Woodcock Johnson was compared between groups [16].

References

  1. Parkinsonism: effects of levodopa treatment on concept formation. Bowen, F.P., Kamienny, R.S., Burns, M.M., Yahr, M. Neurology (1975) [Pubmed]
  2. Neuropsychological dysfunction in schizotypal personality disorder: a profile analysis. Voglmaier, M.M., Seidman, L.J., Salisbury, D., McCarley, R.W. Biol. Psychiatry (1997) [Pubmed]
  3. Depressed mood and executive dysfunction in early Parkinson's disease. Uekermann, J., Daum, I., Peters, S., Wiebel, B., Przuntek, H., Müller, T. Acta neurologica Scandinavica. (2003) [Pubmed]
  4. T-score and raw-score comparisons in detecting brain dysfunction using the booklet category test and the short category test. Gontkovsky, S.T., Souheaver, G.T. Perceptual and motor skills. (2002) [Pubmed]
  5. Cognitive and behavioral effects of the coadministration of dextroamphetamine and haloperidol in schizophrenia. Goldberg, T.E., Bigelow, L.B., Weinberger, D.R., Daniel, D.G., Kleinman, J.E. The American journal of psychiatry. (1991) [Pubmed]
  6. NIDDM and blood pressure as risk factors for poor cognitive performance. The Framingham Study. Elias, P.K., Elias, M.F., D'Agostino, R.B., Cupples, L.A., Wilson, P.W., Silbershatz, H., Wolf, P.A. Diabetes Care (1997) [Pubmed]
  7. Dopa responsive dystonia with Turner's syndrome: clinical, genetic, and neuropsychological studies in a family with a new mutation in the GTP-cyclohydrolase I gene. Nitschke, M., Steinberger, D., Heberlein, I., Otto, V., Müller, U., Vieregge, P. J. Neurol. Neurosurg. Psychiatr. (1998) [Pubmed]
  8. Effects of menstrual phase and parental history of hypertension on cardiovascular response to cognitive challenge. Polefrone, J.M., Manuck, S.B. Psychosomatic medicine. (1988) [Pubmed]
  9. Cognitive impairment in spinocerebellar ataxia type 8. Lilja, A., Hämäläinen, P., Kaitaranta, E., Rinne, R. J. Neurol. Sci. (2005) [Pubmed]
  10. Construct validity of Wechsler factor scores. Livingston, R.B., Gray, R.M., Broquie, J.A., Dickson, T.L., Collins, A.L., Spence, S. Perceptual and motor skills. (2001) [Pubmed]
  11. Factor structure of the Reitan-Indiana Neuropsychological Battery for Children. Livingston, R.B., Gray, R.M., Haak, R.A., Jennings, E. Assessment. (2000) [Pubmed]
  12. The nature and frequency of cognitive deficits in children with neurofibromatosis type 1. Hyman, S.L., Shores, A., North, K.N. Neurology (2005) [Pubmed]
  13. Performance of children diagnosed with ADHD on selected planning and reconstitution tests. Harrier, L.K., DeOrnellas, K. Applied neuropsychology. (2005) [Pubmed]
  14. The neurophysiological basis of learning, Part 2: Concept formation/abstraction, reasoning and executive functions--implications for SCI nurses. Boss, B.J. SCI nursing : a publication of the American Association of Spinal Cord Injury Nurses. (1994) [Pubmed]
  15. Psychopathology in the light of brain injury: a case study. Leftoff, S. Journal of clinical neuropsychology. (1983) [Pubmed]
  16. Anxious-depression in boys: an evaluation of executive functioning. Emerson, C.S., Mollet, G.A., Harrison, D.W. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. (2005) [Pubmed]
 
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