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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Dermoid cyst in the posterior fossa accompanied by Klippel-Feil syndrome.

OBJECTS: Dermoid cysts accompanied by Klippel-Feil syndrome are uncommon, and the coincidence of these two rare diseases suggests an interesting idea about the pathogenesis of a dermoid cyst, which the authors consider with reference to an actual case. A posterior fossa dermoid cyst with dermal sinus and Klippel-Feil syndrome are reported in the same patient. A 23-year-old woman was admitted to hospital with progressive headaches. METHODS: Cervical radiography demonstrated C4-5 vertebral fusion, and magnetic resonance imaging revealed a large cystic mass in the midline of the posterior fossa. The cystic lesion was totally removed along with the accompanying dermal sinus. It was histopathologically diagnosed as a dermoid cyst. CONCLUSION: The rare coincidence of a dermoid cyst and Klippel-Feil syndrome suggests the possibility that a disturbance in the mesoderm before the fourth week of gestation might play an important part in the causation of dermoid cyst.[1]

References

  1. Dermoid cyst in the posterior fossa accompanied by Klippel-Feil syndrome. Hinojosa, M., Tatagiba, M., Harada, K., Samii, M. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. (2001) [Pubmed]
 
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