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Roy H. Perlis

Center for Experimental Drugs and Diagnostics

Massachusetts General Hospital

185 Cambridge St

6th Floor

USA

[email]@partners.org

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Center for Experimental Drugs and Diagnostics, Massachusetts General Hospital, 185 Cambridge St, 6th Floor, USA. 2012
  • Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. 2002 - 2011
  • Bipolar Clinic and Research Programs, 50 Staniford St, 5th Floor, Boston, USA. 2010
  • Pharmacogenetics Research Unit, Depression and Bipolar Clinical and Research Programs, Center for Human Genetics Research, Massachusetts General Hospital, USA. 2007 - 2008
  • Harvard Medical School, 15 Parkman St, AC 812, Boston, USA. 2005 - 2007

References

  1. Do suicidal thoughts or behaviors recur during a second antidepressant treatment trial? Perlis, R.H., Uher, R., Perroud, N., Fava, M. J. Clin. Psychiatry (2012) [Pubmed]
  2. Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder. Perlis, R.H., Uher, R., Ostacher, M., Goldberg, J.F., Trivedi, M.H., Rush, A.J., Fava, M. Arch. Gen. Psychiatry (2011) [Pubmed]
  3. Genome-wide association study of suicide attempts in mood disorder patients. Perlis, R.H., Huang, J., Purcell, S., Fava, M., Rush, A.J., Sullivan, P.F., Hamilton, S.P., McMahon, F.J., Schulze, T.G., Schulze, T., Potash, J.B., Zandi, P.P., Willour, V.L., Penninx, B.W., Boomsma, D.I., Vogelzangs, N., Middeldorp, C.M., Rietschel, M., Nöthen, M., Cichon, S., Gurling, H., Bass, N., McQuillin, A., Hamshere, M., Craddock, N., Sklar, P., Smoller, J.W. Am. J. Psychiatry (2010) [Pubmed]
  4. Benzodiazepine use and risk of recurrence in bipolar disorder: a STEP-BD report. Perlis, R.H., Ostacher, M.J., Miklowitz, D.J., Smoller, J.W., Dennehy, E.B., Cowperthwait, C., Nierenberg, A.A., Thase, M.E., Sachs, G.S. J. Clin. Psychiatry (2010) [Pubmed]
  5. Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder. Perlis, R.H., Smoller, J.W., Mysore, J., Sun, M., Gillis, T., Purcell, S., Rietschel, M., Nöthen, M.M., Witt, S., Maier, W., Iosifescu, D.V., Sullivan, P., Rush, A.J., Fava, M., Breiter, H., Macdonald, M., Gusella, J. Am. J. Psychiatry (2010) [Pubmed]
  6. Genetic association study of treatment response with olanzapine/fluoxetine combination or lamotrigine in bipolar I depression. Perlis, R.H., Adams, D.H., Fijal, B., Sutton, V.K., Farmen, M., Breier, A., Houston, J.P. J. Clin. Psychiatry (2010) [Pubmed]
  7. Clinical features associated with poor pharmacologic adherence in bipolar disorder: results from the STEP-BD study. Perlis, R.H., Ostacher, M.J., Miklowitz, D.J., Hay, A., Nierenberg, A.A., Thase, M.E., Sachs, G.S. J. Clin. Psychiatry (2010) [Pubmed]
  8. When is pharmacogenetic testing for antidepressant response ready for the clinic? A cost-effectiveness analysis based on data from the STAR*D study. Perlis, R.H., Patrick, A., Smoller, J.W., Wang, P.S. Neuropsychopharmacology (2009) [Pubmed]
  9. Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Perlis, R.H., Laje, G., Smoller, J.W., Fava, M., Rush, A.J., McMahon, F.J. Neuropsychopharmacology (2009) [Pubmed]
  10. Irritability is associated with anxiety and greater severity, but not bipolar spectrum features, in major depressive disorder. Perlis, R.H., Fava, M., Trivedi, M.H., Alpert, J., Luther, J.F., Wisniewski, S.R., Rush, A.J. Acta. Psychiatr. Scand (2009) [Pubmed]
  11. Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder. Perlis, R.H., Fijal, B., Adams, D.H., Sutton, V.K., Trivedi, M.H., Houston, J.P. Biol. Psychiatry (2009) [Pubmed]
  12. A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Perlis, R.H., Smoller, J.W., Ferreira, M.A., McQuillin, A., Bass, N., Lawrence, J., Sachs, G.S., Nimgaonkar, V., Scolnick, E.M., Gurling, H., Sklar, P., Purcell, S. Am. J. Psychiatry (2009) [Pubmed]
  13. Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study. Perlis, R.H., Dennehy, E.B., Miklowitz, D.J., Delbello, M.P., Ostacher, M., Calabrese, J.R., Ametrano, R.M., Wisniewski, S.R., Bowden, C.L., Thase, M.E., Nierenberg, A.A., Sachs, G. Bipolar. Disord (2009) [Pubmed]
  14. Stability of symptoms across major depressive episodes in bipolar disorder. Perlis, R.H., Ostacher, M.J., Uher, R., Nierenberg, A.A., Casamassima, F., Kansky, C., Calabrese, J.R., Thase, M., Sachs, G.S. Bipolar. Disord (2009) [Pubmed]
  15. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Perlis, R.H., Moorjani, P., Fagerness, J., Purcell, S., Trivedi, M.H., Fava, M., Rush, A.J., Smoller, J.W. Neuropsychopharmacology (2008) [Pubmed]
  16. Clinical decision making in the treatment of mania. Perlis, R.H. J. Clin. Psychiatry (2008) [Pubmed]
  17. Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder. Perlis, R.H., Purcell, S., Fagerness, J., Cusin, C., Yamaki, L., Fava, M., Smoller, J.W. Biol. Psychiatry (2007) [Pubmed]
  18. Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Perlis, R.H., Purcell, S., Fava, M., Fagerness, J., Rush, A.J., Trivedi, M.H., Smoller, J.W. Arch. Gen. Psychiatry (2007) [Pubmed]
  19. Treatment of bipolar disorder: the evolving role of atypical antipsychotics. Perlis, R.H. Am. J. Manag. Care (2007) [Pubmed]
  20. Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes. Perlis, R.H., Beasley, C.M., Wines, J.D., Tamura, R.N., Cusin, C., Shear, D., Amsterdam, J., Quitkin, F., Strong, R.E., Rosenbaum, J.F., Fava, M. Psychother. Psychosom (2007) [Pubmed]
  21. Use of treatment guidelines in clinical decision making in bipolar disorder: a pilot survey of clinicians. Perlis, R.H. Curr. Med. Res. Opin (2007) [Pubmed]
  22. Pharmacogenetic studies of antidepressant response: how far from the clinic?. Perlis, R.H. Psychiatr. Clin. North Am. (2007) [Pubmed]
  23. Atypical antipsychotics in the treatment of mania: a meta-analysis of randomized, placebo-controlled trials. Perlis, R.H., Welge, J.A., Vornik, L.A., Hirschfeld, R.M., Keck, P.E. J. Clin. Psychiatry (2006) [Pubmed]
  24. Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Perlis, R.H., Ostacher, M.J., Patel, J.K., Marangell, L.B., Zhang, H., Wisniewski, S.R., Ketter, T.A., Miklowitz, D.J., Otto, M.W., Gyulai, L., Reilly-Harrington, N.A., Nierenberg, A.A., Sachs, G.S., Thase, M.E. Am. J. Psychiatry (2006) [Pubmed]
  25. Clinical features of bipolar depression versus major depressive disorder in large multicenter trials. Perlis, R.H., Brown, E., Baker, R.W., Nierenberg, A.A. Am. J. Psychiatry (2006) [Pubmed]
  26. Olanzapine versus risperidone in the treatment of manic or mixed States in bipolar I disorder: a randomized, double-blind trial. Perlis, R.H., Baker, R.W., Zarate, C.A., Brown, E.B., Schuh, L.M., Jamal, H.H., Tohen, M. J. Clin. Psychiatry (2006) [Pubmed]
  27. Prevalence and clinical correlates of irritability in major depressive disorder: a preliminary report from the Sequenced Treatment Alternatives to Relieve Depression study. Perlis, R.H., Fraguas, R., Fava, M., Trivedi, M.H., Luther, J.F., Wisniewski, S.R., Rush, A.J. J. Clin. Psychiatry (2005) [Pubmed]
  28. The role of pharmacologic treatment guidelines for bipolar disorder. Perlis, R.H. J. Clin. Psychiatry (2005) [Pubmed]
  29. The Texas implementation of medication algorithms update for treatment of bipolar I disorder. Perlis, R.H., Keck, P.E. J. Clin. Psychiatry (2005) [Pubmed]
  30. Pharmacogenetic testing in the clinical management of schizophrenia: a decision-analytic model. Perlis, R.H., Ganz, D.A., Avorn, J., Schneeweiss, S., Glynn, R.J., Smoller, J.W., Wang, P.S. J. Clin. Psychopharmacol (2005) [Pubmed]
  31. Revisiting depressive-prone bipolar disorder: polarity of initial mood episode and disease course among bipolar I systematic treatment enhancement program for bipolar disorder participants. Perlis, R.H., Delbello, M.P., Miyahara, S., Wisniewski, S.R., Sachs, G.S., Nierenberg, A.A. Biol. Psychiatry (2005) [Pubmed]
  32. Industry sponsorship and financial conflict of interest in the reporting of clinical trials in psychiatry. Perlis, R.H., Perlis, C.S., Wu, Y., Hwang, C., Joseph, M., Nierenberg, A.A. Am. J. Psychiatry (2005) [Pubmed]
  33. Misdiagnosis of bipolar disorder. Perlis, R.H. Am. J. Manag. Care (2005) [Pubmed]
  34. The prevalence and clinical correlates of anger attacks during depressive episodes in bipolar disorder. Perlis, R.H., Smoller, J.W., Fava, M., Rosenbaum, J.F., Nierenberg, A.A., Sachs, G.S. J. Affect. Disord (2004) [Pubmed]
  35. Effect of medical comorbidity on response to fluoxetine augmentation or dose increase in outpatients with treatment-resistant depression. Perlis, R.H., Iosifescu, D.V., Alpert, J., Nierenberg, A.A., Rosenbaum, J.F., Fava, M. Psychosomatics (2004) [Pubmed]
  36. Biological predictors of treatment response in affective illness. Perlis, R.H., Iosifescu, D.V., Renshaw, P.F. Psychiatr. Clin. North Am. (2003) [Pubmed]
  37. Clinical and sociodemographic predictors of response to augmentation, or dose increase among depressed outpatients resistant to fluoxetine 20 mg/day. Perlis, R.H., Alpert, J., Nierenberg, A.A., Mischoulon, D., Yeung, A., Rosenbaum, J.F., Fava, M. Acta. Psychiatr. Scand (2003) [Pubmed]
  38. Strategies for treatment of SSRI-associated sexual dysfunction: a survey of an academic psychopharmacology practice. Perlis, R.H., Fava, M., Nierenberg, A.A., Pollack, M.H., Falk, W.E., Kienke, A.S., Rosenbaum, J.F. Harv. Rev. Psychiatry (2002) [Pubmed]
  39. Effect of abrupt change from standard to low serum levels of lithium: a reanalysis of double-blind lithium maintenance data. Perlis, R.H., Sachs, G.S., Lafer, B., Otto, M.W., Faraone, S.V., Kane, J.M., Rosenbaum, J.F. Am. J. Psychiatry (2002) [Pubmed]
  40. Effects of adding cognitive therapy to fluoxetine dose increase on risk of relapse and residual depressive symptoms in continuation treatment of major depressive disorder. Perlis, R.H., Nierenberg, A.A., Alpert, J.E., Pava, J., Matthews, J.D., Buchin, J., Sickinger, A.H., Fava, M. J. Clin. Psychopharmacol (2002) [Pubmed]
 
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