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Salvatore Cuzzocrea

Department of Clinical and Experimental Medicine and Pharmacology

School of Medicine

University of Messina

Torre Biologica

Italy

[email]@unime.it

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Clinical and Experimental Medicine and Pharmacology, School of Medicine, University of Messina, Torre Biologica, Italy. 2002 - 2012
  • 1.School of Medicine, University of Messina, Torre Biologica, Policlinico Universitario Via C, Italy. 2012
  • IRCCS Centro Neurolesi "Bonino-Pulejo", S, S, 113 Via Palermo, CTR Casazza, Italy. 2011
  • University of Messina, School of Medicine, Department of Clinical, Experimental Medicine and Pharmacology, Italy. 2008
  • University of Messina, Messina, Italy. 2003 - 2005
  • Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 11/c, 84084 Fisciano-Salerno, Italy. 2004

References

  1. Effect of fasudil, a selective inhibitor of rho kinase activity, in the secondary injury associated with the experimental model of spinal cord trauma. Impellizzeri, D., Mazzon, E., Paterniti, I., Esposito, E., Cuzzocrea, S. J. Pharmacol. Exp. Ther. (2012) [Pubmed]
  2. Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α. Esposito, E., Rinaldi, B., Mazzon, E., Donniacuo, M., Impellizzeri, D., Paterniti, I., Capuano, A., Bramanti, P., Cuzzocrea, S. J. Neuroinflammation (2012) [Pubmed]
  3. Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice. Di Paola, R., Impellizzeri, D., Torre, A., Mazzon, E., Cappellani, A., Faggio, C., Esposito, E., Trischitta, F., Cuzzocrea, S. J. Leukoc. Biol. (2012) [Pubmed]
  4. Oleuropein Aglycone, an Olive Oil Compound, Ameliorates Development of Arthritis Caused by Injection of Collagen Type II in Mice. Impellizzeri, D., Esposito, E., Mazzon, E., Paterniti, I., Di Paola, R., Morittu, V.M., Procopio, A., Britti, D., Cuzzocrea, S. J. Pharmacol. Exp. Ther. (2011) [Pubmed]
  5. New therapeutic strategy for mood disorders. Crupi, R., Marino, A., Cuzzocrea, S. Curr. Med. Chem. (2011) [Pubmed]
  6. Targeting the peroxisome proliferator-activated receptors (PPARs) in spinal cord injury. Esposito, E., Cuzzocrea, S. Expert Opin. Ther. Targets (2011) [Pubmed]
  7. Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis. Di Paola, R., Talero, E., Galuppo, M., Mazzon, E., Bramanti, P., Motilva, V., Cuzzocrea, S. Respir. Res. (2011) [Pubmed]
  8. MK801 attenuates secondary injury in a mouse experimental compression model of spinal cord trauma. Esposito, E., Paterniti, I., Mazzon, E., Genovese, T., Galuppo, M., Meli, R., Bramanti, P., Cuzzocrea, S. BMC. Neurosci (2011) [Pubmed]
  9. CGS 21680, an Agonist of the Adenosine (A2A) Receptor, Reduces Progression of Murine Type II Collagen-induced Arthritis. Mazzon, E., Esposito, E., Impellizzeri, D., DI Paola, R., Melani, A., Bramanti, P., Pedata, F., Cuzzocrea, S. J. Rheumatol. (2011) [Pubmed]
  10. Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. Galuppo, M., Di Paola, R., Mazzon, E., Genovese, T., Crisafulli, C., Paterniti, I., Cuzzocrea, E., Bramanti, P., Kapoor, A., Thiemermann, C., Cuzzocrea, S. J. Inflamm. (Lond) (2010) [Pubmed]
  11. Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma. Cuzzocrea, S., Genovese, T., Mazzon, E., Esposito, E., Di Paola, R., Muià, C., Crisafulli, C., Peli, A., Bramanti, P., Chaudry, I.H. Shock (2008) [Pubmed]
  12. Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids. Cuzzocrea, S., Bruscoli, S., Mazzon, E., Crisafulli, C., Donato, V., Di Paola, R., Velardi, E., Esposito, E., Nocentini, G., Riccardi, C. Mol. Pharmacol. (2008) [Pubmed]
  13. Plant histaminase as an investigational drug in splanchnic artery occlusion and reperfusion. Cuzzocrea, S., Masini, E. Expert. Opin. Investig. Drugs (2008) [Pubmed]
  14. Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut. Cuzzocrea, S., Mazzon, E., Esposito, E., Muià, C., Abdelrahman, M., Di Paola, R., Crisafulli, C., Bramanti, P., Thiemermann, C. Intensive. Care. Med (2007) [Pubmed]
  15. Glycogen synthase kinase-3beta inhibition attenuates the development of bleomycin-induced lung injury. Cuzzocrea, S., Genovese, T., Mazzon, E., Esposito, E., Muià, C., Abdelrahman, M., Di Paola, R., Bramanti, P., Thiemermann, C. Int. J. Immunopathol. Pharmacol (2007) [Pubmed]
  16. Estrogen receptor antagonist fulvestrant (ICI 182,780) inhibits the anti-inflammatory effect of glucocorticoids. Cuzzocrea, S., Bruscoli, S., Crisafulli, C., Mazzon, E., Agostini, M., Muià, C., Esposito, E., Di Virgilio, R., Meli, R., Vegeto, E., Maggi, A., Riccardi, C. Mol. Pharmacol. (2007) [Pubmed]
  17. Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation. Cuzzocrea, S., Ronchetti, S., Genovese, T., Mazzon, E., Agostini, M., Di Paola, R., Esposito, E., Muià, C., Nocentini, G., Riccardi, C. FASEB J. (2007) [Pubmed]
  18. Role of poly(ADP-ribose) glycohydrolase in the development of inflammatory bowel disease in mice. Cuzzocrea, S., Mazzon, E., Genovese, T., Crisafulli, C., Min, W.K., Di Paola, R., Muià, C., Li, J.H., Malleo, G., Xu, W., Massuda, E., Esposito, E., Zhang, J., Wang, Z.Q. Free Radic. Biol. Med. (2007) [Pubmed]
  19. Glycogen synthase kinase 3beta inhibition reduces the development of nonseptic shock induced by zymosan in mice. Cuzzocrea, S., Di Paola, R., Mazzon, E., Crisafulli, C., Genovese, T., Muià, C., Abdelrahman, M., Esposito, E., Thiemermann, C. Shock (2007) [Pubmed]
  20. Inhibition of glycogen synthase kinase-3beta attenuates the development of carrageenan-induced lung injury in mice. Cuzzocrea, S., Crisafulli, C., Mazzon, E., Esposito, E., Muià, C., Abdelrahman, M., Di Paola, R., Thiemermann, C. Br. J. Pharmacol. (2006) [Pubmed]
  21. The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation. Cuzzocrea, S., Mazzon, E., Di Paola, R., Peli, A., Bonato, A., Britti, D., Genovese, T., Muià, C., Crisafulli, C., Caputi, A.P. J. Leukoc. Biol. (2006) [Pubmed]
  22. Peroxisome proliferator-activated receptors and acute lung injury. Cuzzocrea, S. Curr. Opin. Pharmacol (2006) [Pubmed]
  23. Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma. Cuzzocrea, S., Genovese, T., Mazzon, E., Crisafulli, C., Di Paola, R., Muià, C., Collin, M., Esposito, E., Bramanti, P., Thiemermann, C. J. Pharmacol. Exp. Ther. (2006) [Pubmed]
  24. Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse. Cuzzocrea, S., Mazzon, E., Di Paola, R., Muià, C., Crisafulli, C., Dugo, L., Collin, M., Britti, D., Caputi, A.P., Thiemermann, C. Clin. Immunol. (2006) [Pubmed]
  25. Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation. Cuzzocrea, S., Nocentini, G., Di Paola, R., Agostini, M., Mazzon, E., Ronchetti, S., Crisafulli, C., Esposito, E., Caputi, A.P., Riccardi, C. J. Immunol. (2006) [Pubmed]
  26. Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma. Cuzzocrea, S., Genovese, T., Mazzon, E., Crisafulli, C., Min, W., Di Paola, R., Muià, C., Li, J.H., Esposito, E., Bramanti, P., Xu, W., Massuda, E., Zhang, J., Wang, Z.Q. J. Pharmacol. Exp. Ther. (2006) [Pubmed]
  27. Role of nitric oxide and reactive oxygen species in arthritis. Cuzzocrea, S. Curr. Pharm. Des. (2006) [Pubmed]
  28. Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse. Cuzzocrea, S., Mazzon, E., di Paola, R., Genovese, T., Patel, N.S., Britti, D., de Majo, M., Caputi, A.P., Thiemermann, C. Arthritis Rheum. (2005) [Pubmed]
  29. PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion. Cuzzocrea, S., Di Paola, R., Mazzon, E., Cortes, U., Genovese, T., Muià, C., Li, W., Xu, W., Li, J.H., Zhang, J., Wang, Z.Q. FASEB J. (2005) [Pubmed]
  30. 5-Lipoxygenase modulates colitis through the regulation of adhesion molecule expression and neutrophil migration. Cuzzocrea, S., Rossi, A., Mazzon, E., Di Paola, R., Genovese, T., Muià, C., Caputi, A.P., Sautebin, L. Lab. Invest. (2005) [Pubmed]
  31. Shock, inflammation and PARP. Cuzzocrea, S. Pharmacol. Res. (2005) [Pubmed]
  32. Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion. Cuzzocrea, S., Wang, Z.Q. Pharmacol. Res. (2005) [Pubmed]
  33. Effects of combination M40403 and dexamethasone therapy on joint disease in a rat model of collagen-induced arthritis. Cuzzocrea, S., Mazzon, E., Paola, R.D., Genovese, T., Muià, C., Caputi, A.P., Salvemini, D. Arthritis Rheum. (2005) [Pubmed]
  34. Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice. Di Paola, R., Mazzon, E., Muià, C., Genovese, T., Menegazzi, M., Zaffini, R., Suzuki, H., Cuzzocrea, S. Respir. Res. (2005) [Pubmed]
  35. Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis. Cuzzocrea, S., Ayroldi, E., Di Paola, R., Agostini, M., Mazzon, E., Bruscoli, S., Genovese, T., Ronchetti, S., Caputi, A.P., Riccardi, C. FASEB J. (2005) [Pubmed]
  36. Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance. Cuzzocrea, S., Mazzon, E., di Paola, R., Genovese, T., Muià, C., Caputi, A.P., Salvemini, D. Arthritis Rheum. (2005) [Pubmed]
  37. Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation. Cuzzocrea, S., Pisano, B., Dugo, L., Ianaro, A., Maffia, P., Patel, N.S., Di Paola, R., Ialenti, A., Genovese, T., Chatterjee, P.K., Di Rosa, M., Caputi, A.P., Thiemermann, C. Eur. J. Pharmacol. (2004) [Pubmed]
  38. Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein. Cuzzocrea, S., Pisano, B., Dugo, L., Ianaro, A., Britti, D., Patel, N.S., Di Paola, R., Genovese, T., Di Rosa, M., Caputi, A.P., Thiemermann, C. Intensive. Care. Med (2004) [Pubmed]
  39. Potential therapeutic effect of antioxidant therapy in shock and inflammation. Cuzzocrea, S., Thiemermann, C., Salvemini, D. Curr. Med. Chem. (2004) [Pubmed]
  40. High-density lipoproteins reduce the intestinal damage associated with ischemia/reperfusion and colitis. Cuzzocrea, S., Dugo, L., Patel, N.S., Di Paola, R., Cockerill, G.W., Genovese, T., Thiemermann, C. Shock (2004) [Pubmed]
  41. Role of 5-lipoxygenase in the multiple organ failure induced by zymosan. Cuzzocrea, S., Rossi, A., Serraino, I., Di Paola, R., Dugo, L., Genovese, T., Britti, D., Sciarra, G., De Sarro, A., Caputi, A.P., Sautebin, L. Intensive. Care. Med (2004) [Pubmed]
  42. Erythropoietin reduces the development of experimental inflammatory bowel disease. Cuzzocrea, S., Mazzon, E., Di Paola, R., Patel, N.S., Genovese, T., Muià, C., De Sarro, A., Thiemermann, C. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  43. Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock. Cuzzocrea, S., Nocentini, G., Di Paola, R., Mazzon, E., Ronchetti, S., Genovese, T., Muià, C., Caputi, A.P., Riccardi, C. J. Leukoc. Biol. (2004) [Pubmed]
  44. WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock. Cuzzocrea, S., Di Paola, R., Mazzon, E., Genovese, T., Muià, C., Caputi, A.P. Shock (2004) [Pubmed]
  45. Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-alpha) in the development of inflammatory bowel disease in mice. Cuzzocrea, S., Di Paola, R., Mazzon, E., Genovese, T., Muià, C., Centorrino, T., Caputi, A.P. Lab. Invest. (2004) [Pubmed]
  46. Tempol reduces the activation of nuclear factor-kappaB in acute inflammation. Cuzzocrea, S., Pisano, B., Dugo, L., Ianaro, A., Patel, N.S., Caputi, A.P., Thiemermann, C. Free Radic. Res. (2004) [Pubmed]
  47. 5-Aminoisoquinolinone reduces colon injury by experimental colitis. Cuzzocrea, S., Mazzon, E., Di Paola, R., Genovese, T., Patel, N.S., Muià, C., Threadgill, M.D., De Sarro, A., Thiemermann, C. Naunyn Schmiedebergs Arch. Pharmacol. (2004) [Pubmed]
  48. Effect of methylguanidine in a model of septic shock induced by LPS. Marzocco, S., Di Paola, R., Ribecco, M.T., Sorrentino, R., Domenico, B., Genesio, M., Pinto, A., Autore, G., Cuzzocrea, S. Free Radic. Res. (2004) [Pubmed]
  49. Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury. Cuzzocrea, S. Vascul. Pharmacol. (2004) [Pubmed]
  50. Inducible nitric oxide synthase mediates bone loss in ovariectomized mice. Cuzzocrea, S., Mazzon, E., Dugo, L., Genovese, T., Di Paola, R., Ruggeri, Z., Vegeto, E., Caputi, A.P., Van De Loo, F.A., Puzzolo, D., Maggi, A. Endocrinology (2003) [Pubmed]
  51. The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat. Cuzzocrea, S., Ianaro, A., Wayman, N.S., Mazzon, E., Pisano, B., Dugo, L., Serraino, I., Di Paola, R., Chatterjee, P.K., Di Rosa, M., Caputi, A.P., Thiemermann, C. Br. J. Pharmacol. (2003) [Pubmed]
  52. 5-Lipoxygenase knockout mice exhibit a resistance to pleurisy and lung injury caused by carrageenan. Cuzzocrea, S., Rossi, A., Serraino, I., Mazzon, E., Di Paola, R., Dugo, L., Genovese, T., Calabrò, B., Caputi, A.P., Sautebin, L. J. Leukoc. Biol. (2003) [Pubmed]
  53. 5-lipoxygenase knockout mice exhibit a resistance to splanchnic artery occlusion shock. Cuzzocrea, S., Rossi, A., Serraino, I., Di Paola, R., Dugo, L., Genovese, T., Caputi, A.P., Sautebin, L. Shock (2003) [Pubmed]
  54. 5-lipoxygenase knockout mice exhibit a resistance to acute pancreatitis induced by cerulein. Cuzzocrea, S., Rossi, A., Serraino, I., Di Paola, R., Dugo, L., Genovese, T., Britti, D., Sciarra, G., De Sarro, A., Caputi, A.P., Sautebin, L. Immunology (2003) [Pubmed]
  55. Emerging biotherapies for inflammatory bowel disease. Cuzzocrea, S. Expert. Opin. Emerg. Drugs (2003) [Pubmed]
  56. Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma. Cuzzocrea, S., Mazzon, E., Dugo, L., Patel, N.S., Serraino, I., Di Paola, R., Genovese, T., Britti, D., De Maio, M., Caputi, A.P., Thiemermann, C. Arthritis Rheum. (2003) [Pubmed]
  57. The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. Cuzzocrea, S., Wayman, N.S., Mazzon, E., Dugo, L., Di Paola, R., Serraino, I., Britti, D., Chatterjee, P.K., Caputi, A.P., Thiemermann, C. Mol. Pharmacol. (2002) [Pubmed]
 
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