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Silke Appel-Dingemanse

Clinical Pharmacology Department

Novartis Pharma AG

CH-4002 Basel



Name/email consistency: high



  • Clinical Pharmacology Department, Novartis Pharma AG, CH-4002 Basel, Switzerland. 2001 - 2002
  • Novartis Pharma AG, Basel, Switzerland. 2001


  1. Clinical pharmacokinetics of tegaserod, a serotonin 5-HT(4) receptor partial agonist with promotile activity. Appel-Dingemanse, S. Clin. Pharmacokinet (2002) [Pubmed]
  2. Multiple-dose pharmacokinetics confirm no accumulation and dose proportionality of the novel promotile drug tegaserod (HTF 919). Appel-Dingemanse, S., Hirschberg, Y., Osborne, S., Pommier, F., McLeod, J. Eur. J. Clin. Pharmacol. (2001) [Pubmed]
  3. The pharmacokinetics of the novel promotile drug, tegaserod, are similar in healthy subjects-male and female, elderly and young. Appel-Dingemanse, S., Horowitz, A., Campestrini, J., Osborne, S., McLeod, J. Aliment. Pharmacol. Ther. (2001) [Pubmed]
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