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Robert Siman

Department of Pharmacology

University of Pennsylvania School of Medicine

Philadelphia

Pennsylvania 19104

USA

[email]@*.med.upenn.edu

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Affiliation

Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. 2000 - 2005

References

Novel surrogate markers for acute brain damage: cerebrospinal fluid levels corrrelate with severity of ischemic neurodegeneration in the rat. Siman, R., Zhang, C., Roberts, V.L., Pitts-Kiefer, A., Neumar, R.W. J. Cereb. Blood Flow Metab. (2005) [Pubmed]
Proteins released from degenerating neurons are surrogate markers for acute brain damage. Siman, R., McIntosh, T.K., Soltesz, K.M., Chen, Z., Neumar, R.W., Roberts, V.L. Neurobiol. Dis. (2004) [Pubmed]
Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain. Siman, R., Salidas, S. Neuroscience (2004) [Pubmed]
Localization of presenilin-nicastrin complexes and gamma-secretase activity to the trans-Golgi network. Siman, R., Velji, J. J. Neurochem. (2003) [Pubmed]
Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation. Siman, R., Flood, D.G., Thinakaran, G., Neumar, R.W. J. Biol. Chem. (2001) [Pubmed]
Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability. Siman, R., Reaume, A.G., Savage, M.J., Trusko, S., Lin, Y.G., Scott, R.W., Flood, D.G. J. Neurosci. (2000) [Pubmed]