Barbara C. Spink
Laboratory of Molecular Toxicology
Wadsworth Center
New York State Department of Health
Albany
USA
Name/email consistency: high
- Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells. Spink, B.C., Bennett, J.A., Pentecost, B.T., Lostritto, N., Englert, N.A., Benn, G.K., Goodenough, A.K., Turesky, R.J., Spink, D.C. Toxicol. Appl. Pharmacol. (2009)
- Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. Spink, D.C., Wu, S.J., Spink, B.C., Hussain, M.M., Vakharia, D.D., Pentecost, B.T., Kaminsky, L.S. Toxicol. Appl. Pharmacol. (2008)
- Inhibition of MCF-7 breast cancer cell proliferation by MCF-10A breast epithelial cells in coculture. Spink, B.C., Cole, R.W., Katz, B.H., Gierthy, J.F., Bradley, L.M., Spink, D.C. Cell Biol. Int. (2006)
- Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells. Spink, D.C., Katz, B.H., Hussain, M.M., Pentecost, B.T., Cao, Z., Spink, B.C. Carcinogenesis (2003)
- Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite. Spink, D.C., Katz, B.H., Hussain, M.M., Spink, B.C., Wu, S.J., Liu, N., Pause, R., Kaminsky, L.S. Drug Metab. Dispos. (2002)
- Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells. Spink, D.C., Zhang, F., Hussain, M.M., Katz, B.H., Liu, X., Hilker, D.R., Bolton, J.L. Chem. Res. Toxicol. (2001)
- SULT1A1 catalyzes 2-methoxyestradiol sulfonation in MCF-7 breast cancer cells. Spink, B.C., Katz, B.H., Hussain, M.M., Pang, S., Connor, S.P., Aldous, K.M., Gierthy, J.F., Spink, D.C. Carcinogenesis (2000)
- NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1. Spink, D.C., Spink, B.C., Zhuo, X., Hussain, M.M., Gierthy, J.F., Ding, X. J. Steroid Biochem. Mol. Biol. (2000)