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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Stephen H. Safe

Corresponding Author: Stephen Safe

Department of Veterinary Physiology and Pharmacology

Texas A&M University

4466 TAMU


Name/email consistency: high



  • Corresponding Author: Stephen Safe, Department of Veterinary Physiology and Pharmacology, Texas A&M University, 4466 TAMU. 1997 - 2012
  • Institute of Biosciences and Technology, Texas A and M University System Health Science Center, 2121 W. Holcombe Blvd., Houston, USA. 2005


  1. Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters. Kim, K., Chadalapaka, G., Pathi, S.S., Jin, U.H., Lee, J.S., Park, Y.Y., Cho, S.G., Chintharlapalli, S., Safe, S. Mol. Cancer Ther. (2012) [Pubmed]
  2. Aryl Hydrocarbon Receptor (AHR)-Active Pharmaceuticals Are Selective AHR Modulators in MDA-MB-468 and BT474 Breast Cancer Cells. Jin, U.H., Lee, S.O., Safe, S. J. Pharmacol. Exp. Ther. (2012) [Pubmed]
  3. Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer. Liu, X., Jutooru, I., Lei, P., Kim, K., Lee, S.O., Brents, L.K., Prather, P.L., Safe, S. Mol. Cancer Ther. (2012) [Pubmed]
  4. Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells. Zhang, S., Kim, K., Jin, U.H., Pfent, C., Cao, H., Amendt, B., Liu, X., Wilson-Robles, H., Safe, S. Mol. Cancer Ther. (2012) [Pubmed]
  5. Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. Sreevalsan, S., Joseph, S., Jutooru, I., Chadalapaka, G., Safe, S.H. Anticancer Res. (2011) [Pubmed]
  6. Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors. Chintharlapalli, S., Papineni, S., Lei, P., Pathi, S., Safe, S. BMC. Cancer (2011) [Pubmed]
  7. 3-methylcholanthrene induces differential recruitment of aryl hydrocarbon receptor to human promoters. Safe, S. Toxicol. Sci. (2010) [Pubmed]
  8. Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs. Safe, S., Papineni, S., Chintharlapalli, S. Cancer Lett. (2008) [Pubmed]
  9. Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. Safe, S., Kim, K., Kim, K. J. Mol. Endocrinol. (2008) [Pubmed]
  10. The role of xenoestrogenic compounds in the development of breast cancer. Safe, S., Papineni, S. Trends Pharmacol. Sci. (2006) [Pubmed]
  11. Clinical correlates of environmental endocrine disruptors. Safe, S. Trends Endocrinol. Metab. (2005) [Pubmed]
  12. Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins. Abdelrahim, M., Safe, S. Mol. Pharmacol. (2005) [Pubmed]
  13. Sp transcription factor family and its role in cancer. Safe, S., Abdelrahim, M. Eur. J. Cancer (2005) [Pubmed]
  14. Endocrine disruptors and human health: is there a problem. Safe, S. Toxicology (2004) [Pubmed]
  15. Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action. Safe, S., Wormke, M. Chem. Res. Toxicol. (2003) [Pubmed]
  16. Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers (Review). Safe, S., McDougal, A. Int. J. Oncol. (2002) [Pubmed]
  17. Environmental estrogens: roles in male reproductive tract problems and in breast cancer. Safe, S. Rev. Environ. Health (2002) [Pubmed]
  18. Problems for risk assessment of endocrine-active estrogenic compounds. Safe, S.H., Pallaroni, L., Yoon, K., Gaido, K., Ross, S., McDonnell, D. Environ. Health Perspect. (2002) [Pubmed]
  19. Molecular biology of the Ah receptor and its role in carcinogenesis. Safe, S. Toxicol. Lett. (2001) [Pubmed]
  20. Toxicology of environmental estrogens. Safe, S.H., Pallaroni, L., Yoon, K., Gaido, K., Ross, S., Saville, B., McDonnellc, D. Reprod. Fertil. Dev. (2001) [Pubmed]
  21. Bisphenol A and related endocrine disruptors. Safe, S. Toxicol. Sci. (2000) [Pubmed]
  22. Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells. Safe, S., Wormke, M., Samudio, I. J. Mammary. Gland. Biol. Neoplasia (2000) [Pubmed]
  23. Symposium on mechanisms of action of naturally occurring anticarcinogens. Safe, S., Wargovich, M.J., Lamartiniere, C.A., Mukhtar, H. Toxicol. Sci. (1999) [Pubmed]
  24. Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer. Safe, S., Qin, C., McDougal, A. Expert. Opin. Investig. Drugs (1999) [Pubmed]
  25. Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms. Safe, S., Wang, F., Porter, W., Duan, R., McDougal, A. Toxicol. Lett. (1998) [Pubmed]
  26. Methods for xenoestrogen testing. Safe, S., Connor, K., Gaido, K. Toxicol. Lett. (1998) [Pubmed]
  27. Interactions between hormones and chemicals in breast cancer. Safe, S.H. Annu. Rev. Pharmacol. Toxicol. (1998) [Pubmed]
  28. Estrogen- and antiestrogen-responsiveness of HEC1A endometrial adenocarcinoma cells in culture. Castro-Rivera, E., Safe, S. J. Steroid Biochem. Mol. Biol. (1998) [Pubmed]
  29. Is there an association between exposure to environmental estrogens and breast cancer?. Safe, S.H. Environ. Health Perspect. (1997) [Pubmed]
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