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Shakil A. Saghir

Toxicology & Environmental Research and Consulting

The Dow Chemical Company

1803 Building

Midland

USA

[email]@dow.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Toxicology & Environmental Research and Consulting, The Dow Chemical Company, 1803 Building, Midland, USA. 2003 - 2011
  • Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, USA. 2005

References

  1. Kinetics of trihalogenated acetic Acid metabolism and isoform specificity in liver microsomes. Saghir, S.A., Ghanayem, B.I., Schultz, I.R. Int. J. Toxicol. (2011) [Pubmed]
  2. In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis. Saghir, S.A., Zhang, F., Rick, D.L., Kan, L., Bus, J.S., Bartels, M.J. Regul. Toxicol. Pharmacol. (2010) [Pubmed]
  3. Dermal penetration of ethylene glycol through human skin in vitro. Saghir, S.A., Bartels, M.J., Snellings, W.M. Int. J. Toxicol. (2010) [Pubmed]
  4. Mechanism of ethylbenzene-induced mouse-specific lung tumor: metabolism of ethylbenzene by rat, mouse, and human liver and lung microsomes. Saghir, S.A., Rick, D.L., McClymont, E.L., Zhang, F., Bartels, M.J., Bus, J.S. Toxicol. Sci. (2009) [Pubmed]
  5. Simulation of repeated dose kinetics of methyl isobutyl ketone in humans from experimental single-dose inhalation exposure. Saghir, S.A., Rick, D.L. Regul. Toxicol. Pharmacol. (2008) [Pubmed]
  6. Mechanism of trifluralin-induced thyroid tumors in rats. Saghir, S.A., Charles, G.D., Bartels, M.J., Kan, L.H., Dryzga, M.D., Brzak, K.A., Clark, A.J. Toxicol. Lett. (2008) [Pubmed]
  7. Pharmacokinetics of aminomethylpropanol in rats following oral and a novel dermal study design. Saghir, S.A., Clark, A.J., McClymont, E.L., Staley, J.L. Food Chem. Toxicol. (2008) [Pubmed]
  8. Effect of organic carbon content, clay type, and aging on the oral bioavailability of hexachlorobenzene in rats. Saghir, S.A., Bartels, M.J., Budinsky, R.A., Harris, E.E., Clark, A.J., Staley, J.L., Chai, Y., Davis, J.W. Environ. Toxicol. Chem. (2007) [Pubmed]
  9. Pharmacokinetics and bioavailability of diisopropanolamine (DIPA) in rats following intravenous or dermal application. Saghir, S.A., Frantz, S.W., Spence, M.W., Nolan, R.J., Lowe, E.R., Rick, D.L., Bartels, M.J. Food Chem. Toxicol. (2007) [Pubmed]
  10. Strategies to assess systemic exposure of chemicals in subchronic/chronic diet and drinking water studies. Saghir, S.A., Mendrala, A.L., Bartels, M.J., Day, S.J., Hansen, S.C., Sushynski, J.M., Bus, J.S. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  11. Investigation of the formation of N-nitrosodiethanolamine in B6C3F1 mice following topical administration of triethanolamine. Saghir, S.A., Brzak, K.A., Markham, D.A., Bartels, M.J., Stott, W.T. Regul. Toxicol. Pharmacol. (2005) [Pubmed]
  12. Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state. Saghir, S.A., Lebofsky, M., Pinson, D.M., Rozman, K.K. Toxicology (2005) [Pubmed]
  13. Oral absorption, metabolism and excretion of 1-phenoxy-2-propanol in rats. Saghir, S.A., Brzak, K.A., Bartels, M.J. Xenobiotica (2003) [Pubmed]
 
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